PANCREAZE is a combination of porcine-derived lipases, proteases, amylases indicated for the treatment of exocrine pancreatic insufficiency due to cystic fibrosis or other conditions.

Savings and Support

 
 

A FREE, comprehensive support program

Explore the broad range of support services, monthly savings and offers for patients and caregivers.

 

Significantly improved access for commercially insured patients

As of January 1st, 2021:

PANCREAZE is now covered on over 80% of commercial insurance plans — including preferred brand status on multiple plans!

Source: Managed Markets Insight & Technology, LLC, database as of February, 2021. Certain plans may require prior authorization.

Check your plan for details or use our lookup tool below

 
 

PANCREAZE Engage also offers help for eligible PANCREAZE patients unable to pay for their medication. Eligible patients can apply for assistance and receive their medication at no-cost.

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*Patient Co-Pay Eligibility, Terms, and Conditions

Eligible patients may pay a minimum of $0 and receive up to $100 off the patient’s co-pay or out-of-pocket expenses for a 30-day supply of PANCREAZE (pancrelipase) capsules. Patient Instructions: In order to redeem the offer, you must have a valid prescription for PANCREAZE. This offer may not be redeemed for cash. By using this offer, you are certifying that you meet the eligibility criteria and will comply with the terms and conditions below.

Terms and conditions: Offer is not transferable. Patients are not eligible if they are covered in whole or in part by any state program or federal healthcare program, including, but not limited to, Medicare or Medicaid (including Medicaid managed care), Medigap, VA, DOD,or TRICARE. Only valid in the United States, Puerto Rico, Guam and the U.S. Virgin Islands. Offer void where prohibited by law, taxed, or restricted. Other restrictions may apply. This program is not health insurance. VIVUS, Inc. has the right to rescind, revoke, or amend this program at any time without notice. Your participation in this program confirms that this offer is consistent with your insurance coverage and that you will report the value received if required by your insurance provider. When you use this card, you are certifying that you understand and will comply with the program rules, terms, and conditions.

**Savings for Patients Paying Cash

Patients may be eligible for this offer if they are not insured and are responsible for the cost of their prescriptions. Eligible patients may save up to $200 off out-of-pocket costs for a 30-day supply of PANCREAZE (pancrelipase) capsules. Savings will vary depending on the dose of PANCREAZE that your doctor prescribes for you. Patients taking the 16,800 or 21,000 lipase unit doses will save up to $200 on a 30-day supply every month and patients taking the 2,600, 4,200 or 10,500 lipase unit doses will save up to $67 on a 30-day supply every month.

Patient Instructions: In order to redeem this offer you must have a valid prescription for PANCREAZE. This offer may not be redeemed for cash and may not be used in combination with any other discount, coupon, rebate, free trial, or similar offer.

Terms and conditions: The card must be presented at the time the prescription is filled and dispensed to the patient for instant savings. The card is limited to one per person and good for up to 1 use per month and is not transferable. Patients who present this card at participating pharmacies will save up to $200 off their out-of-pocket costs for their PANCREAZE prescription each month. The patient is responsible for applicable taxes and any remaining out-of-pocket costs, if any. Patients are not eligible if they are covered in whole or in part by any state program or federal healthcare program, including, but not limited to, Medicare or Medicaid (including Medicaid managed care), Medigap, VA, DOD, or TRICARE. Patients, pharmacists, and prescribers cannot seek reimbursement from health insurance or any third party for any part of the amount received by the patient through this offer. When you use the card, you are certifying that you meet the eligibility criteria and will comply with the program rules, terms, and conditions. This program is not health insurance and is only valid in the United States, Puerto Rico, Guam and the U.S. Virgin Islands. Void where prohibited by law, taxed, or restricted. Other restrictions may apply. VIVUS has the right to rescind, revoke, or amend this program at any time without notice.

PANCREAZE Patient Assistance Program Requirements

  • The patient does not have insurance or their medication is not covered
    • Please note, some patients with Medicare Prescription Drug Coverage (Part D) who cannot afford their medication and who meet certain financial criteria may also be eligible for assistance
      • In order to qualify for the program, the patient must spend 4% or more of their gross annual income on prescription drugs
         
  • The patient’s income level is equal to or less than 300% above the U.S. Federal Poverty Guidelines
  • The patient lives in the United States or a U.S. Territory
  • The patient is being treated for EPI by a U.S. licensed healthcare provider as an outpatient

Online VIVUS Health Store and Program Terms

VIVUS provides eligible Pancreaze patients or caregivers of eligible patients under the age of 18, a monthly discount. Eligible patients or caregivers of eligible patients will be issued Shopify single-use savings codes on a monthly basis that can be redeemed and applied to the purchase of products available in the VIVUS Health Store. VIVUS reserves the right to expire these savings codes at any time, delete or modify the amount of the benefit, and change the products offered in its store. By registering for the PANCREAZE Engage program, and by using this site, you are authorizing VIVUS or its designee to contact you by telephone, direct mail or email in order to receive the benefits and verify continued eligibility. VIVUS reserves the right to revoke eligibility and access to these monthly codes based upon proof of prescription and/or PANCREAZE use.

Indication

PANCREAZE is a prescription medicine used to treat people who cannot digest food normally because their pancreas does not make enough enzymes due to cystic fibrosis or other conditions. PANCREAZE may help your body use fats, proteins, and sugars from food.

Important Safety Information

What is the most important information I should know about PANCREAZE?​

PANCREAZE may increase your chance of having a serious, rare bowel disorder called fibrosing colonopathy that may require surgery. The risk of having this condition may be reduced by following the dosing instructions that your healthcare provider gave you.

Take PANCREAZE exactly as prescribed by your doctor. Do not take more or less PANCREAZE than directed by your doctor.

Call your doctor right away if you have any unusual or severe stomach area (abdominal) pain, bloating, trouble passing stool (having bowel movements), nausea, vomiting, or diarrhea.

What should I tell my doctor before taking PANCREAZE?

Tell your doctor if you:

  • are allergic to pork (pig) products
  • have a history of blockage of your intestines, or scarring or thickening of your bowel wall (fibrosing colonopathy)
  • have gout, kidney disease, or high blood uric acid (hyperuricemia)
  • have trouble swallowing capsules
  • have any other medical condition
  • are pregnant or plan to become pregnant
  • are breastfeeding or plan to breastfeed

Tell your doctor about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements.

What are the possible side effects of PANCREAZE?

PANCREAZE may cause serious side effects, including:

  • A rare bowel disorder called fibrosing colonopathy
  • Irritation of the inside of your mouth. This can happen if PANCREAZE is not swallowed completely
  • Increase in blood uric acid levels. This may cause worsening of swollen, painful joints (gout) caused by an increase in your blood uric acid levels
  • Allergic reactions including trouble with breathing, skin rashes, or swollen lips

The most common side effects include pain in your stomach (abdominal pain) and gas.

These are not all the side effects of PANCREAZE. Talk to your doctor about any side effect that bothers you or does not go away. You may report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. You may also report side effects to VIVUS, Inc. at 1-888-998-4887.

How do I take PANCREAZE?

  • Do not crush or chew the PANCREAZE capsules or their contents, and do not hold the capsule or contents in your mouth. Take PANCREAZE exactly as your doctor tells you. Read the Medication Guide for directions on how to give PANCREAZE to adults and children (children older than 12 months).
  • Read the Medication Guide for directions on how to give PANCREAZE to infants (children up to 12 months).

Please read the PANCREAZE Medication Guide and PANCREAZE Product Information and discuss any questions you have with your doctor.

References: 1. PANCREAZE Full Prescribing Information. Campbell, CA: VIVUS, Inc; 2020. 2. Pezilli R, et al. Exocrine pancreatic insufficiency in adults: A shared position statement of the Italian association for the study of the pancreas. World J Gastroenterol. 2013;19 (44):7930-7946. 3. Lindkvist B. Diagnosis and treatment of pancreatic exocrine insufficiency. World J Gastroenterol. 2013;19(42):7258-7266. 4. The Cystic Fibrosis Foundation (n.d.). About Cystic Fibrosis. Retrieved from https://www.cff.org/What-is-CF/About-Cystic-Fibrosis/ 5. Struyvenberg MR, et al. Practical guide to exocrine pancreatic insufficiency - breaking the myths. BMC Med. 2017;15(1):29. 6. Othman MO, et al. Introduction and practical approach to exocrine pancreatic insufficiency for the practicing clinician. Int J Clin Pract. .2018;72:e13066. 7. The National Pancreas Foundation (n.d.). About Chronic Pancreatitis. Retrieved from https://pancreasfoundation.org/patient-information/chronic-pancreatitis/ 8. CREON® Full Prescribing Information. Chicago, IL: Abvie, Inc; 2015 . 9. PERTZYE® Full Prescribing Information. Bethlehem, PA: Digestive Care, Inc; 2017. 10. ULTRESA® Full Prescribing Information. Bridgewater, NJ: Aptalis Pharma US, Inc; 2011. 11. VIOKACE™ Full Prescribing Information. Birmingham, AL: Allergan USA, Inc; 2012. 12. ZENPEP® Full Prescribing Information. Irvine, CA: Allergan USA, Inc; 2017.

Important Safety Information

PANCREAZE may increase your chance of having a serious, rare bowel disorder called fibrosing colonopathy that may require surgery. The risk of having this condition may be reduced by following the dosing instructions that your healthcare provider gave you. Take PANCREAZE exactly as prescribed by your doctor. Do not take more or less PANCREAZE than directed by your doctor.

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